Leyton Orient London vs Wycombe Wanderers Prediction & Betting Tips - League One

Prediction published on 24/04/2025, 06:30  by Ian John in League One Predictions

There are few games as important as the League One clash between Leyton Orient and Wycombe Wanderers this weekend. The O’s currently hold the final playoff spot on goal difference, while the visiting Chairboys lie third in the table, two points adrift of the automatic promotion spots. Given that both teams will feel a win is a must, what will our prediction be for this potentially season-defining match?

Heading into this crucial fixture, Leyton Orient’s recent improved form has seen them catch and move above Reading into sixth and the playoff spots, with 72 points from 44 games and a +20 goal difference. Wycombe dropped to third over the weekend out of the automatic promotion spots. They have 84 points from 44 games and lie two points ahead of Charlton, three in front of Stockport, but two behind Wrexham in second.

With six wins in their last eight, including all their last four, Leyton Orient have hit form at the right time. Three of those wins came on the road. They won their last home game in dramatic fashion, coming from 3-1 down to beat Barnsley 4-3 and then at the weekend won 2-1 away to Cambridge United.

Wycombe had been in good form too, winning 1-0 against Huddersfield (away) and Stevenage (home) before earning a 2-0 win at Bolton. But at the weekend, the Chairboys were thrashed 4-0 at home by Charlton Athletic, which saw them drop out of the automatic promotion slots.