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by Lou Aguila | in MLB Picks
Paul Skenes and the Pittsburgh Pirates will play host to the St. Louis Cardinals in Game 2 of their three-game series at PNC Park on Tuesday.
The Pirates scored back-to-back wins over the New York Yankees 5-4 and St. Louis Cardinals 8-4 to raise their record to 4-7. Ironically, Pittsburgh has the seventh worst ERA in baseball at 4.89 ahead of Paul Skene’s third start of the season vs. the Cardinals. The reigning National League Rookie of the Year bounced back from a subpar season debut by shutting out the Tampa Bay Rays through seven innings while striking out six batters in a 4-2 win on April 3.
The Cardinals slipped to 4-6 after losing their four games, including Monday’s series-opener vs. the Pirates 4-8. St. Louis is batting a league-high .297 with 66 runs this season. But despite wielding one of the most prolific offenses in the league, the Cardinals could not reap much gains because their league-worst ERA of 6.18 is costing them from winning games.
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St. Louis Cardinals vs Pittsburgh Pirates Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
15
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0.5 | 18 | 9 | 9 |
26
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0.368 | 19 | 7 | 12 |
St. Louis Cardinals and Pittsburgh Pirates Latest Matches

1/6 (17%)
5/6 (83%)
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 6, 2025 - MLB
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
4/6 (67%)
2/6 (33%)
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 27, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 6, 2025 - MLB
Apr 4, 2025 - MLB
Mar 24, 2025 - MLB Spring Training
Mar 22, 2025 - MLB Spring Training

3/6 (50%)
3/6 (50%)
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Mar 22, 2025 - MLB Spring Training
Mar 18, 2025 - MLB Spring Training
2/6 (33%)
4/6 (67%)
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 28, 2025 - MLB
St. Louis Cardinals against Pittsburgh Pirates : Head to Head (H2H)
50 %
50 %
Apr 7, 2025 - MLB
Sep 19, 2024 - MLB
Sep 18, 2024 - MLB
Sep 17, 2024 - MLB
Sep 16, 2024 - MLB
Jul 24, 2024 - MLB
St. Louis Cardinals - Pittsburgh Pirates Key Points
- Paul Skenes is 1-0 with a 1.46 ERA this season.
- Paul Skenes has 13 strikeouts this season.
- Paul Skenes is 0-2 with a 1.21 ERA and 23 strikeouts in three games vs. the Cardinals last season.
- Paul Skenes is the reigning National League Rookie of the Year.
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Our St. Louis Cardinals vs Pittsburgh Pirates Prediction
Paul Skenes hasn’t recorded more than 10 strikeouts this season. In his rookie year, the Pirates ace had two games of 10+ strikeouts and a bundle of games with at least 8 strikeouts. DraftKings has pegged a +115 for a Paul Skenes 8+ strikeouts showing on Tuesday. The Cardinals are an aggressive, offensive team that isn’t shy of swinging for the fences as often as possible. This is an opportunity for Skenes to test St. Louis sluggers and hopefully collect more than eight strikeouts in a single game after collecting seven and six Ks in his last two starts. Our betting prediction for St. Louis Cardinals vs. Pittsburgh Pirates: Paul Skenes 8+ Strikeouts.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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