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by Lou Aguila in MLB Picks
National League Central rivals St. Louis Cardinals and Pittsburgh Pirates face off for the first time this season at PNC Park on Sunday.
Cardinals will attempt to recover from a three-game sweep dealt by the Boston Red Sox in the previous series. St. Louis comes into Pittsburgh ranking inside the top-5 in batting average (.301), on-base percentage (.380), slugging percentage (.482) and total runs (62). They are a high-scoring squad that is struggling to hold off teams from scoring runs because of their erratic pitching. St. Louis has posted a league-worst 6.01 ERA through 9 games.
Meanwhile, the Pirates squashed the Yankees’ attempt to sweep the series as Tommy Pham delivered an RBI single to cap Pittsburgh’s three-run rally in the 11th inning of a 5-4 win. Pittsburgh is batting .197 with 32 runs, which rank in the lower quadrant of the league. The Pirates are also among the worst teams in pitching department, throwing a 4.98 ERA with a 1.46 WHIP and .266 BAA.
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St. Louis Cardinals vs Pittsburgh Pirates Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
26
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0.4 | 25 | 10 | 15 |
27
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0.385 | 26 | 10 | 16 |
St. Louis Cardinals and Pittsburgh Pirates Latest Matches

1/6 (17%)
5/6 (83%)
Apr 6, 2025 - MLB
Apr 6, 2025 - MLB
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
4/6 (67%)
2/6 (33%)
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 27, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 6, 2025 - MLB
Apr 6, 2025 - MLB
Apr 4, 2025 - MLB
Mar 24, 2025 - MLB Spring Training
Mar 22, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training

2/6 (33%)
4/6 (67%)
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Mar 22, 2025 - MLB Spring Training
Mar 18, 2025 - MLB Spring Training
Mar 17, 2025 - MLB Spring Training
2/6 (33%)
4/6 (67%)
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 28, 2025 - MLB
St. Louis Cardinals against Pittsburgh Pirates : Head to Head (H2H)
67 %
33 %
Sep 19, 2024 - MLB
Sep 18, 2024 - MLB
Sep 17, 2024 - MLB
Sep 16, 2024 - MLB
Jul 24, 2024 - MLB
Jul 23, 2024 - MLB
St. Louis Cardinals - Pittsburgh Pirates Key Points
- St. Louis are 9-3 SU in their last 12 games against an opponent in the National League.
- St. Louis are 8-4 SU in their last 12 games against Pittsburgh.
- Pittsburgh are 2-6 SU in their last 8 games.
- Pittsburgh are 1-4 SU in their last 5 games against an opponent in the National League.
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Our St. Louis Cardinals vs Pittsburgh Pirates Prediction
Despite their 1-5 record in their last six games, St. Louis carry a winning record in their last 12 meeting with Pittsburgh at 8-4. The Cardinals are also dispatching left-handed pitcher Matthew Liberatore for Monday’s series opener. Honestly, I don’t expect much from Liberatore after throwing three runs in six innings in a 7-9 loss to the LA Angels on April 1. However, I still think he would deliver better numbers than Pirates starter Carmin Mlodzinski, who comes into Monday’s ballgame with a 9.82 ERA after surrendering four earned runs vs. the Dodgers. A high-scoring matchup is likely since we have two starters who allowed too many runs in their previous starts. I still feel the Cardinals have an edge in this game because of their high-powered offense. Our betting prediction for St. Louis Cardinals vs. Pittsburgh Pirates: St. Louis Cardinals will cover -1.5 runs.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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