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by Travis Pulver | in MLB Picks
It will not be easy to get back on the right side of the scoreboard against a red-hot San Diego Padres team, but the Houston Astros will try in Game One of a three-game home series tonight at Daiken Park in Houston, TX. First pitch is scheduled for 8:10 p.m. EST.
Houston has been struggling to get on track this season; through 18 games, they have yet to win two in a row. The only time they have lost 2+ in a row was a three-game sweep vs. San Francisco. They have one of the lowest team batting averages of the season at .216. But their pitching staff has been one of the best in baseball with a 3.73 ERA (top ten) and 181 strikeouts (fourth best). San Diego, on the other hand, has the best batting average in the league at .274. Their pitching staff has also been top-notch, with a 2.56 ERA and a 1.07 WHIP, while holding opponents to a .193 batting average.
San Diego will turn to Kyle Hart to start the game on the mound for the Padres. In three starts, he’s gone 2-0 with a 5.40 ERA and 1.11 WHIP. Ryan Gusto will get the start for Houston. He appears to be more of an opener, having gone just 2, 2, 3,1, and 4 innings in five starts.
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San Diego Padres vs Houston Astros Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
1
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0.75 | 20 | 15 | 5 |
18
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0.474 | 19 | 9 | 10 |
San Diego Padres and Houston Astros Latest Matches

5/6 (83%)
1/6 (17%)
Apr 16, 2025 - MLB
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
5/6 (83%)
1/6 (17%)
Apr 16, 2025 - MLB
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB

3/6 (50%)
3/6 (50%)
Apr 16, 2025 - MLB
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 16, 2025 - MLB
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
San Diego Padres against Houston Astros : Head to Head (H2H)
83 %
17 %
Sep 18, 2024 - MLB
Sep 17, 2024 - MLB
Sep 16, 2024 - MLB
Sep 4, 2021 - MLB
Aug 23, 2020 - MLB
Aug 22, 2020 - MLB
San Diego Padres - Houston Astros Key Points
- Houston leads the all-time series vs. San Diego 320-296.
- The Padres have gone 10-5 vs. the Astros over the last four seasons.
- This will be the first time either pitcher has faced the opposing team.
- Houston has lost 14 of their last 15 games following a road loss.
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Our San Diego Padres vs Houston Astros Prediction
If the pattern holds, Houston is due for a win, but they are facing a decent pitcher against a potent lineup. Tack on the suspect production coming from their lineup and it becomes a lot harder to justify getting behind the Astros. However, if this is a bullpen game for Houston, the ‘pen’s ERA is 2.94, and they have been playing better at home….
Our Astros vs. Padres Pick: San Diego ML
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