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by Stephen Abiola | in MLB Picks
St. Louis Cardinals and Minnesota Twins are embroiled in a thrilling three-game series at Busch Stadium. The Cardinals come into this matchup hoping to find some success after a couple of disappointing campaigns by their own standards. They finished 2023 with a 71-91 record before slightly improving in 2024 to post an 83-79 record. The Cardinals have also missed the playoffs for two straight seasons, the first time since the 2016-2018 campaigns. They are under pressure to improve this season.
Likewise, Minnesota Twins experienced a frustrating 2025 MLB campaign, finishing the regular season with an 82-80 record. They have missed the postseason campaign thrice in the previous four seasons, a record they'll be eager to rectify in 2025. Minnesota Twins have been busy during the offseason, bringing in outfielder Harrison Bader and first baseman Ty France to strengthen the team. A playoff return could be on the horizon if they manage to stay healthy.
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Minnesota Twins vs St. Louis Cardinals Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
1
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1 | 3 | 3 | 0 |
27
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0 | 4 | 0 | 4 |
Minnesota Twins and St. Louis Cardinals Latest Matches

3/6 (50%)
3/6 (50%)
Mar 27, 2025 - MLB
Mar 25, 2025 - MLB Spring Training
Mar 24, 2025 - MLB Spring Training
Mar 23, 2025 - MLB Spring Training
Mar 22, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 25, 2025 - MLB Spring Training
Mar 24, 2025 - MLB Spring Training
Mar 22, 2025 - MLB Spring Training
Mar 20, 2025 - MLB Spring Training
Mar 18, 2025 - MLB Spring Training
Mar 16, 2025 - MLB Spring Training
2/6 (33%)
4/6 (67%)
Mar 27, 2025 - MLB
Mar 23, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training
Mar 17, 2025 - MLB Spring Training
Mar 15, 2025 - MLB Spring Training
Mar 14, 2025 - MLB Spring Training

3/6 (50%)
3/6 (50%)
Mar 27, 2025 - MLB
Mar 24, 2025 - MLB Spring Training
Mar 23, 2025 - MLB Spring Training
Mar 22, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 27, 2025 - MLB
Mar 23, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training
Mar 19, 2025 - MLB Spring Training
Mar 18, 2025 - MLB Spring Training
Mar 15, 2025 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 24, 2025 - MLB Spring Training
Mar 22, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training
Mar 17, 2025 - MLB Spring Training
Mar 16, 2025 - MLB Spring Training
Mar 14, 2025 - MLB Spring Training
Minnesota Twins against St. Louis Cardinals : Head to Head (H2H)
33 %
67 %
Mar 27, 2025 - MLB
Aug 25, 2024 - MLB
Aug 24, 2024 - MLB
Aug 23, 2024 - MLB
Aug 3, 2023 - MLB
Sep 8, 2020 - MLB
Minnesota Twins - St. Louis Cardinals Key Points
- The Twins had an average of 4.4 runs away from home last season.
- The Cardinals had an average of 4.1 runs at home last season.
- The total runs went over in the last five Minnesota games against NL teams.
- Minnesota Twins won against the run line in three of their previous six matches.
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Our Minnesota Twins vs St. Louis Cardinals Prediction
We're going to take the Twins in this matchup. Not only are they the better team right now, but they also have a lot to prove this season. Their starting pitcher, Pablo Lopez, should give them an edge in most matches this season, boasting a 15-10 record with an ERA of 4.08. The Cardinals, meanwhile, could struggle after the departure of Paul Goldschmidt. This could see them miss the postseason, although they'll be fired up to prove their doubters wrong. They'll also aim to surprise everyone with an NL Central Title. We expect a very tight contest here. Our prediction for St. Louis Cardinals vs Minnesota Twins: Over 7.5 runs.
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