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by Lou Aguila in MLB Picks
The Cleveland Guardians and the Minnesota Twins are heading into Wednesday’s Game 3 at Progressive Field with the series tied after splitting the first two games.
The Twins’ four-game winning streak ended on Tuesday as Chris Paddack and company stifled Minnesota batters. Minnesota sits in fourth place in the American League Central with a 13-17 record, batting .233 with 118 runs and pitching 3.51 in the season.
The Guardians earned their first win in four matches behind an exceptional mound performance from their pitching staff. Chris Paddack allowed one earned run in 5.0 inning while Emmanuel Clase bagged his fourth save of the season after securing the last three outs in the 9th inning. Cleveland is second in the AL Central with 16-13 record, 1.5 games behind the 18-12 Detroit Tigers.
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Minnesota Twins vs Cleveland Guardians Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
9
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0.552 | 29 | 16 | 13 |
22
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0.433 | 30 | 13 | 17 |
Minnesota Twins and Cleveland Guardians Latest Matches

4/6 (67%)
2/6 (33%)
Apr 29, 2025 - MLB
Apr 28, 2025 - MLB
Apr 27, 2025 - MLB
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Apr 24, 2025 - MLB
5/6 (83%)
1/6 (17%)
Apr 27, 2025 - MLB
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Apr 22, 2025 - MLB
1/6 (17%)
5/6 (83%)
Apr 29, 2025 - MLB
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Apr 19, 2025 - MLB
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Apr 10, 2025 - MLB

2/6 (33%)
4/6 (67%)
Apr 29, 2025 - MLB
Apr 28, 2025 - MLB
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
Apr 26, 2025 - MLB
Apr 23, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 29, 2025 - MLB
Apr 28, 2025 - MLB
Apr 27, 2025 - MLB
Apr 26, 2025 - MLB
Apr 26, 2025 - MLB
Apr 23, 2025 - MLB
4/6 (67%)
2/6 (33%)
Apr 20, 2025 - MLB
Apr 19, 2025 - MLB
Apr 18, 2025 - MLB
Apr 17, 2025 - MLB
Apr 16, 2025 - MLB
Apr 15, 2025 - MLB
Minnesota Twins against Cleveland Guardians : Head to Head (H2H)
33 %
67 %
Apr 29, 2025 - MLB
Apr 28, 2025 - MLB
Sep 19, 2024 - MLB
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Sep 16, 2024 - MLB
Minnesota Twins - Cleveland Guardians Key Points
- Minnesota is 4-1 SU in its last 5 games.
- Minnesota is 4-12 SU in its last 16 games against Cleveland.
- Cleveland is 2-4 SU in its last 6 games.
- Cleveland is 8-2 SU in its last 10 games when playing at home against Minnesota.
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Our Minnesota Twins vs Cleveland Guardians Prediction
Fearless Forecast: Minnesota Twins strike back to take Game 3 by at least two runs.
I picked the Twins to win and cover -1.5 runs against the Guardians in Game 3 with the expectation of a solid outing from Pablo Lopez (2.30 ERA), who is posting a 2.00 ERA over his last three starts vs. the Guardians. I like Lopez’s chance of winning his duel with the Guardians’ projected starter, Luiz Lopez (5.96 ERA), mainly because Lopez has been unpredictable on the mound this season. For the second straight start, Lopez collected 8 strikeouts but threw away four earned runs in 4.1 innings in a 1-5 loss to the Yankees on April 23. Meanwhile, Minnesota holds a 4-1 SU record in its last 5 games and a 3-1 slate against the spread in its previous four games. Our betting prediction for the Minnesota Twins vs. the Cleveland Guardians: Twins -1.5 Runs
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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