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by Carlos Zabala | in MLB Picks
The betting sites weren't wrong when they set a close game for the first game of the Angels-Cardinals series, even though St. Louis had swept the Twins in the opening series. The game was tied by just one run for much of the game. Kyren Paris hit a triple for the Angels that tied the game, extending it into extra innings, where the Angels would score two runs in the tenth to close out a 4-5 victory for the visitors.
Trout didn't hit a hit in three at-bats but drove in two runs via two sacrifice flies. Soler and Moncada went 1-for-8, but despite that and the Angels striking out 10 times, they earned a valuable win, which puts their record at 3-1 in 2025.
The Cardinals went with their veteran starter for Game 1, but for Game 2, the Angels will start Tuesday's game with 35-year-old Kyle Hendricks, well known to the Cardinals. It will be a historic game for Hendricks after leaving the Cubs after 11 uninterrupted seasons with them.
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Los Angeles Angels vs St. Louis Cardinals Form
Table
Teams | % | P | W | L |
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3
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0.8 | 5 | 4 | 1 |
11
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0.6 | 5 | 3 | 2 |
Los Angeles Angels and St. Louis Cardinals Latest Matches

4/6 (67%)
2/6 (33%)
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
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Mar 25, 2025 - MLB Spring Training
Mar 24, 2025 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 25, 2025 - MLB Spring Training
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Mar 19, 2025 - MLB Spring Training
Mar 16, 2025 - MLB Spring Training
Mar 15, 2025 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 27, 2025 - MLB
Mar 23, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training

4/6 (67%)
2/6 (33%)
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 27, 2025 - MLB
Mar 24, 2025 - MLB Spring Training
Mar 23, 2025 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 27, 2025 - MLB
Mar 23, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 24, 2025 - MLB Spring Training
Mar 22, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training
Mar 17, 2025 - MLB Spring Training
Mar 16, 2025 - MLB Spring Training
Mar 14, 2025 - MLB Spring Training
Los Angeles Angels against St. Louis Cardinals : Head to Head (H2H)
50 %
50 %
Mar 31, 2025 - MLB
May 15, 2024 - MLB
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Jun 23, 2019 - MLB
Jun 21, 2019 - MLB
Los Angeles Angels - St. Louis Cardinals Key Points
- In 2024, Hendricks posted his highest ERA ever at 5.92
- The Cardinals struck out 9 times and walked 4 in a loss to the Angels
- Three of the Cardinals' four games this year resulted in a Game Total Over
- Arenado has had at least one hit with the Cardinals in every game so far in 2025
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Our Los Angeles Angels vs St. Louis Cardinals Prediction
At odds of around -150, the Cards will be favorites to win the game, although it could very well be a close call considering the Angels' last three games were decided by one run. Liberatore, the 25-year-old left-hander, will be the starting pitcher for the home team. Oliver Marmol said he will give Liberatore an extended run in 2025 to prove his worth as a starter. Our prediction for Angels vs Cardinals is: Over 8.5 runs.
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