USA - NFL

Indianapolis Colts
29 Dec 2025 13:00
New York Giants

Prediction:

 

Colts -7.5

-105
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Indianapolis Colts vs New York Giants Prediction & Picks - NFL

 by Travis Pulver | in NFL Picks

The Colts will try to keep their slim playoff hopes alive this week when they host the New York Giants at Luca Oil Stadium in Indianapolis. Kickoff is scheduled for 1 p.m. ET. Indianapolis. The Colts opened as two-point favorites, but the line has extended to 7.5 points. However, if Anthony Richardson is unable to go and Joe Flacco gets the start, the line is bound to move again.

Then again, it may not matter who plays quarterback for the Colts. The Giants rank second to last in run defense this season. Indianapolis has one of the best running backs in the NFL, who exploded for 218 yards last week. Much of it came on two long touchdown runs (70 and 65 yards). New York has given up the second most runs of 20+ yards (18) and the most of 40+ (5). If Richardson can play, it gives the Colts a two-pronged run game, but if he does not, they will have a better shot at a passing game with Flacco. New York will start Drew Lock at quarterback despite the two pick-6s he threw last week.

The Giants are barely averaging two touchdowns a game this season, but they are far from being the lowest-scoring offense of all time (1992 Seahawks, 8.8 ppg).

Indianapolis Colts vs New York Giants Form

Table

Teams % P W D L
19
Indianapolis Colts
Indianapolis Colts
0.467 15 7 0 8
32
New York Giants
New York Giants
0.133 15 2 0 13

Indianapolis Colts and New York Giants Latest Matches

Indianapolis Colts
Indianapolis Colts Latest matches
L W L W L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Dec 22, 2024 - NFL

Tennessee Titans
30 :  38
Indianapolis Colts

Dec 15, 2024 - NFL

Indianapolis Colts
13 :  31
Denver Broncos

Dec 1, 2024 - NFL

Indianapolis Colts
25 :  24
New England Patriots

Nov 24, 2024 - NFL

Detroit Lions
24 :  6
Indianapolis Colts

Nov 17, 2024 - NFL

Indianapolis Colts
28 :  27
New York Jets

Nov 10, 2024 - NFL

Buffalo Bills
30 :  20
Indianapolis Colts
W W W L L W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Dec 22, 2024 - NFL

Tennessee Titans
30 :  38
Indianapolis Colts

Nov 24, 2024 - NFL

Detroit Lions
24 :  6
Indianapolis Colts

Nov 10, 2024 - NFL

Buffalo Bills
30 :  20
Indianapolis Colts

Oct 20, 2024 - NFL

Miami Dolphins
10 :  16
Indianapolis Colts

Sep 29, 2024 - NFL

Pittsburgh Steelers
24 :  27
Indianapolis Colts

Sep 22, 2024 - NFL

Chicago Bears
16 :  21
Indianapolis Colts
W L L W W L
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Dec 15, 2024 - NFL

Indianapolis Colts
13 :  31
Denver Broncos

Dec 1, 2024 - NFL

Indianapolis Colts
25 :  24
New England Patriots

Nov 17, 2024 - NFL

Indianapolis Colts
28 :  27
New York Jets

Nov 3, 2024 - NFL

Indianapolis Colts
13 :  21
Minnesota Vikings

Oct 27, 2024 - NFL

Indianapolis Colts
20 :  23
Houston Texans

Oct 13, 2024 - NFL

Indianapolis Colts
20 :  17
Tennessee Titans
New York Giants
New York Giants Latest matches
L L L L L L
Victories

0/6 (0%)

Draw

0/6 (0%)

Defeats

6/6 (100%)

Dec 22, 2024 - NFL

New York Giants
7 :  34
Atlanta Falcons

Dec 15, 2024 - NFL

Baltimore Ravens
35 :  14
New York Giants

Dec 8, 2024 - NFL

New Orleans Saints
14 :  11
New York Giants

Nov 28, 2024 - NFL

New York Giants
20 :  27
Dallas Cowboys

Nov 24, 2024 - NFL

Tampa Bay Buccaneers
30 :  7
New York Giants

Nov 10, 2024 - NFL

New York Giants
17 :  20
Carolina Panthers
L L L L L L
Victories

0/6 (0%)

Draw

0/6 (0%)

Defeats

6/6 (100%)

Dec 15, 2024 - NFL

Baltimore Ravens
35 :  14
New York Giants

Dec 8, 2024 - NFL

New Orleans Saints
14 :  11
New York Giants

Nov 24, 2024 - NFL

Tampa Bay Buccaneers
30 :  7
New York Giants

Nov 3, 2024 - NFL

Washington Commanders
27 :  22
New York Giants

Oct 20, 2024 - NFL

Philadelphia Eagles
28 :  3
New York Giants

Oct 13, 2024 - NFL

Cincinnati Bengals
17 :  7
New York Giants
W W L L L L
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Dec 22, 2024 - NFL

New York Giants
7 :  34
Atlanta Falcons

Nov 28, 2024 - NFL

New York Giants
20 :  27
Dallas Cowboys

Nov 10, 2024 - NFL

New York Giants
17 :  20
Carolina Panthers

Oct 28, 2024 - NFL

New York Giants
18 :  26
Pittsburgh Steelers

Oct 6, 2024 - NFL

New York Giants
29 :  20
Seattle Seahawks

Sep 22, 2024 - NFL

New York Giants
21 :  15
Cleveland Browns

Indianapolis Colts - New York Giants Key Points

  1. The Colts lead the all-time series with the Giants, 12-8.
  2. The Giants last won at home in Week 18 of last season, 27-10 over the Eagles.
  3. To make the playoffs, the Colts need to win out, for the Dolphins to win out, and for the Broncos to lose out.
  4. With only two wins this season, the Giants are projected to have the No. 1 pick in the next draft.

Our Indianapolis Colts vs New York Giants Prediction

Whether the Colts start Anthony Richardson or Joe Flacco, Indianapolis should have no problem winning this game. No matter who they have at quarterback, the passing game doesn’t work, and whatever magic Tyrone Tracy Jr. had appears to have expired. He hasn’t gained more than 45 yards in a game since running for 103 yards vs. Carolina in Munich (Week 10). To be fair, the Colts offense hasn’t been too reliable, either. But there is more reason to have hope they’ll put some offense together than the Giants. Indianapolis will improve to .500 with a win in this game.

Our Colts vs. Giants Pick: Colts -7.5

Prediction:

 

Colts -7.5

-105
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Indianapolis Colts vs New York Giants Picks