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by Lou Aguila | in MLB Picks
The Houston Astros aim for their first win streak this season in Wednesday’s series-finale against the St. Louis Cardinals at Busch Stadium.
The up and down pattern continues for the Astros, who bounced back from 3-8 loss in Game 1 vs. the Cardinals by bagging their first team shutout win of the season. Hunter Brown was sensational on the mound for six innings, allowing four hits and two walks to garner his second consecutive shutout. Houston is sporting a 3.92 ERA, which falls in the middle of the pack, but their bullpen has figured it out in the last five games, surrendering a 1.42 ERA.
The Game 2 loss snapped the Cardinals’ two-game winning run, absorbing their first shutout loss this year. Batting .280 with 5.3 runs per game, St. Louis could only produce six hits against the Astros’ impeccable pitching on Tuesday.
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Houston Astros vs St. Louis Cardinals Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
18
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0.471 | 17 | 8 | 9 |
18
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0.471 | 17 | 8 | 9 |
Houston Astros and St. Louis Cardinals Latest Matches

3/6 (50%)
3/6 (50%)
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 9, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB

3/6 (50%)
3/6 (50%)
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 9, 2025 - MLB
4/6 (67%)
2/6 (33%)
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 2, 2025 - MLB
1/6 (17%)
5/6 (83%)
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 6, 2025 - MLB
Apr 4, 2025 - MLB
Houston Astros against St. Louis Cardinals : Head to Head (H2H)
67 %
33 %
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Mar 21, 2025 - MLB Spring Training
Mar 13, 2025 - MLB Spring Training
Mar 7, 2025 - MLB Spring Training
Mar 5, 2025 - MLB Spring Training
Houston Astros - St. Louis Cardinals Key Points
- Houston are 1-4 SU in their last 5 games against an opponent in the National League.
- Houston are 5-2 SU in their last 7 games when playing on the road against St. Louis.
- St. Louis are 2-5 SU in their last 7 games when playing at home against Houston.
- St. Louis are 1-4 SU in their last 5 games against an opponent in the American League.
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Our Houston Astros vs St. Louis Cardinals Prediction
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