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by Carlos Zabala | in MLB Picks
Game 2 between the Astros and Cardinals on Tuesday in Houston has the Astros as slight favorites at -130 odds, with Hunter Brown starting for them and Erick Fedde for the Cardinals.
The Astros also closed the pre-Game 1 betting round as a -115 favorite but ended up losing 3-8. The Astros have already lost more games as favorites in 2025 than they have won, with a 4-6 record. Meanwhile, the Cardinals are one of the most lucrative underdogs in MLB, with a 7-4 record in those games.
Arenado is batting 280 to start 2025 and hit his second home run of the season in the bottom of the seventh inning, but in Monday's 8-3 win, it was Donovan, batting in the bottom of the lineup, who had the better game, going 4-for-4 and scoring two runs in a game where the Cards allowed 14 hits.
Erick Fedde is coming off a strong start against the Pirates at PNC Park, where he pitched six scoreless innings on 88 pitches. However, his offense didn't back him up, and the Cardinals would end up losing their last outing 2-1.
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Houston Astros vs St. Louis Cardinals Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
17
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0.474 | 19 | 9 | 10 |
20
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0.444 | 18 | 8 | 10 |
Houston Astros and St. Louis Cardinals Latest Matches

3/6 (50%)
3/6 (50%)
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 14, 2025 - MLB
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB

4/6 (67%)
2/6 (33%)
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
4/6 (67%)
2/6 (33%)
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
1/6 (17%)
5/6 (83%)
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 6, 2025 - MLB
Apr 4, 2025 - MLB
Houston Astros against St. Louis Cardinals : Head to Head (H2H)
67 %
33 %
Apr 14, 2025 - MLB
Mar 21, 2025 - MLB Spring Training
Mar 13, 2025 - MLB Spring Training
Mar 7, 2025 - MLB Spring Training
Mar 5, 2025 - MLB Spring Training
Feb 28, 2025 - MLB Spring Training
Houston Astros - St. Louis Cardinals Key Points
- Sonny Gray pitched 7 scoreless innings for the Cardinals in Game 1 against the Astros
- Hunter Brown threw over 90 pitches in his first 3 starts of 2025
- The Cardinals are averaging 5.8 runs per 9 innings against right-handed pitchers in 2025
- The Astros are only averaging 7.2 hits per game this season
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Our Houston Astros vs St. Louis Cardinals Prediction
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