USA - NCAA Basketball

Creighton
3/20/25 12:15
Louisville Cardinals

Prediction:

 

Louisville ML

-140
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Creighton vs Louisville Cardinals Prediction & Picks - NCAA Basketball

 by Matt Lowrimore | in Basketball Picks

The first game of the NCAA tournament first round on Thursday will see the 9th-seeded Creighton Bluejays take on the 8th-seeded Louisville Cardinals in the South Region. Let’s take a look at the match statistics and predictions for this first-round game between the Bluejays and Cardinals to see who will advance to the Round of 32 over the weekend.

Creighton enters this game with a record of 24-10. They beat DePaul in the Big East quarterfinals, and UConn in the Big East semifinals before losing to St. John’s in the Big East final. Creighton will be making their 26th NCAA tournament appearance and their 5th consecutive appearance.

As for Louisville, they enter this game with a record of 27-7. The Cardinals beat Stanford in the ACC quarterfinals, Clemson in the ACC semifinals before losing to Duke in the ACC final. Louisville is making their 44th NCAA tournament appearance and their first appearance since the 2018-2019 season.

Creighton vs Louisville Cardinals Form

Creighton and Louisville Cardinals Latest Matches

Creighton
Creighton Latest matches
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 15, 2025 - NCAA Men

Creighton
66 :  82
St. John's Red Storm

Mar 14, 2025 - NCAA Men

UCONN
62 :  71
Creighton

Mar 13, 2025 - NCAA Men

DePaul Blue Demons
81 :  85
Creighton

Mar 8, 2025 - NCAA Men

Butler Bulldogs
74 :  87
Creighton

Mar 4, 2025 - NCAA Men

Creighton
79 :  61
Seton Hall Pirates

Mar 1, 2025 - NCAA Men

Creighton
61 :  83
Xavier Musketeers
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Mar 14, 2025 - NCAA Men

UCONN
62 :  71
Creighton

Mar 13, 2025 - NCAA Men

DePaul Blue Demons
81 :  85
Creighton

Mar 8, 2025 - NCAA Men

Butler Bulldogs
74 :  87
Creighton

Feb 26, 2025 - NCAA Men

DePaul Blue Demons
65 :  75
Creighton

Feb 23, 2025 - NCAA Men

Georgetown Hoyas
69 :  80
Creighton

Feb 11, 2025 - NCAA Men

UCONN
70 :  66
Creighton
W W L L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Mar 15, 2025 - NCAA Men

Creighton
66 :  82
St. John's Red Storm

Mar 4, 2025 - NCAA Men

Creighton
79 :  61
Seton Hall Pirates

Mar 1, 2025 - NCAA Men

Creighton
61 :  83
Xavier Musketeers

Feb 16, 2025 - NCAA Men

Creighton
73 :  79
St. John's Red Storm

Feb 5, 2025 - NCAA Men

Creighton
80 :  69
Providence Friars

Feb 1, 2025 - NCAA Men

Creighton
62 :  60
Villanova Wildcats
Louisville Cardinals
Louisville Cardinals Latest matches
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Mar 15, 2025 - NCAA Men

Louisville Cardinals
62 :  73
Duke

Mar 14, 2025 - NCAA Men

Clemson
73 :  76
Louisville Cardinals

Mar 13, 2025 - NCAA Men

Stanford Cardinal
73 :  75
Louisville Cardinals

Mar 8, 2025 - NCAA Men

Stanford Cardinal
48 :  68
Louisville Cardinals

Mar 5, 2025 - NCAA Men

California Golden Bears
68 :  85
Louisville Cardinals

Mar 1, 2025 - NCAA Men

Pittsburgh Panthers
68 :  79
Louisville Cardinals
W W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Mar 14, 2025 - NCAA Men

Clemson
73 :  76
Louisville Cardinals

Mar 13, 2025 - NCAA Men

Stanford Cardinal
73 :  75
Louisville Cardinals

Mar 8, 2025 - NCAA Men

Stanford Cardinal
48 :  68
Louisville Cardinals

Mar 5, 2025 - NCAA Men

California Golden Bears
68 :  85
Louisville Cardinals

Mar 1, 2025 - NCAA Men

Pittsburgh Panthers
68 :  79
Louisville Cardinals

Feb 22, 2025 - NCAA Men

Florida State Seminoles
81 :  89
Louisville Cardinals
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 15, 2025 - NCAA Men

Louisville Cardinals
62 :  73
Duke

Feb 25, 2025 - NCAA Men

Louisville Cardinals
71 :  66
Virginia Tech Hokies

Feb 16, 2025 - NCAA Men

Louisville Cardinals
75 :  60
Notre Dame Fighting Irish

Feb 12, 2025 - NCAA Men

Louisville Cardinals
91 :  66
NC St.

Feb 5, 2025 - NCAA Men

Louisville Cardinals
84 :  58
Boston College Eagles

Feb 1, 2025 - NCAA Men

Louisville Cardinals
70 :  77
Georgia Tech Yellow Jackets

Creighton - Louisville Cardinals Key Points

  1. Louisville is 4-2 ATS in their last 6 games
  2. Louisville is 11-1 SU in their last 12 games
  3. Louisville is 5-1 SU in their last 6 March games
  4. Louisville is 10-0 SU in their last 10 games as a favorite

Our Creighton vs Louisville Cardinals Prediction

There is something to be said about how much Louisville has improved since last season. The Cardinals were a miserable 8-24 in 2023-2024 and now have made the NCAA tournament with a chance to make a deep run. Louisville’s offense has improved significantly, averaging 79.1 points per game, which is top 60 in the country this season.

Creighton also has a top-tier offense but the difference is that they tend to be too reliant on the three-point shot. The Bluejays average nearly 28 three-point shots per game but shoot only about 34%. All it would take is for Creighton to have an off-day shooting and they may not have the inside or mid-range scoring to keep up. Because Creighton relies on the three-point shot too much, our Creighton Bluejays vs Louisville Cardinals prediction is Louisville ML.

Prediction:

 

Louisville ML

-140
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Creighton vs Louisville Cardinals Picks