Cleveland Guardians vs San Diego Padres Prediction & Picks - MLB

See our betting tips for the next match between these two teams
Cleveland Guardians - San Diego Padres Betting tips

USA - MLB

Cleveland Guardians
4/1/25 21:40
San Diego Padres

Prediction:

 

Over 7.5 runs.

-114
$150 offered for betting!

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 by Carlos Zabala | in MLB Picks

Nearly all of the Padres' bats to start 2025 have contributed well for a team looking to keep pace against the Dodgers. In Monday's game, the Padres scored four runs in the second inning off Tatis, driving in two of them with a hit. However, the Guardians also brought Dominican power, and, returning to the lineup after spraining his wrist against the Royals, José Ramírez hit his first home run of the season.

Betting odds placed the Padres as favorites for Game 2 at around -165 over the Guardians hours before the Game 1 playoff even began. For the second game of the series at Petco, between two of the most effective home teams in 2024, Allen will start for the Guardians and King for the Padres in what could be a pitching duel.

In King's first start this season, the Padres won 7-4 at Petco Park, but King did not even pitch 3 innings against the Braves, allowing 3 ER and giving 4 BB, filling up with pitches very quickly, and an even more ruthless lineup awaits him in the Guardians' bats on Tuesday.

Cleveland Guardians vs San Diego Padres Form

Table

Teams % P W L
1
San Diego Padres
San Diego Padres
1 6 6 0
15
Cleveland Guardians
Cleveland Guardians
0.4 5 2 3

Cleveland Guardians and San Diego Padres Latest Matches

Cleveland Guardians
Cleveland Guardians Latest matches
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 31, 2025 - MLB

Cleveland Guardians
2 :  7
San Diego Padres

Mar 30, 2025 - MLB

Cleveland Guardians
6 :  2
Kansas City Royals

Mar 29, 2025 - MLB

Cleveland Guardians
3 :  4
Kansas City Royals

Mar 27, 2025 - MLB

Cleveland Guardians
7 :  4
Kansas City Royals

Mar 25, 2025 - MLB Spring Training

Cleveland Guardians
3 :  2
Arizona Diamondbacks

Mar 24, 2025 - MLB Spring Training

Cleveland Guardians
4 :  3
Arizona Diamondbacks
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Mar 22, 2025 - MLB Spring Training

San Diego Padres
8 :  12
Cleveland Guardians

Mar 19, 2025 - MLB Spring Training

Athletics
8 :  3
Cleveland Guardians

Mar 17, 2025 - MLB Spring Training

Cincinnati Reds
0 :  3
Cleveland Guardians

Mar 14, 2025 - MLB Spring Training

Seattle Mariners
7 :  8
Cleveland Guardians

Mar 12, 2025 - MLB Spring Training

San Francisco Giants
11 :  2
Cleveland Guardians

Mar 10, 2025 - MLB Spring Training

Chicago Cubs
7 :  4
Cleveland Guardians
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 31, 2025 - MLB

Cleveland Guardians
2 :  7
San Diego Padres

Mar 30, 2025 - MLB

Cleveland Guardians
6 :  2
Kansas City Royals

Mar 29, 2025 - MLB

Cleveland Guardians
3 :  4
Kansas City Royals

Mar 27, 2025 - MLB

Cleveland Guardians
7 :  4
Kansas City Royals

Mar 25, 2025 - MLB Spring Training

Cleveland Guardians
3 :  2
Arizona Diamondbacks

Mar 24, 2025 - MLB Spring Training

Cleveland Guardians
4 :  3
Arizona Diamondbacks
San Diego Padres
San Diego Padres Latest matches
D W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Mar 31, 2025 - MLB

Cleveland Guardians
2 :  7
San Diego Padres

Mar 30, 2025 - MLB

Atlanta Braves
0 :  5
San Diego Padres

Mar 29, 2025 - MLB

Atlanta Braves
0 :  1
San Diego Padres

Mar 28, 2025 - MLB

Atlanta Braves
3 :  4
San Diego Padres

Mar 27, 2025 - MLB

Atlanta Braves
4 :  7
San Diego Padres

Mar 24, 2025 - MLB Spring Training

Seattle Mariners
7 :  7
San Diego Padres
D W W W W W
Victories

6/6 (100%)

Defeats

0/6 (0%)

Mar 31, 2025 - MLB

Cleveland Guardians
2 :  7
San Diego Padres

Mar 30, 2025 - MLB

Atlanta Braves
0 :  5
San Diego Padres

Mar 29, 2025 - MLB

Atlanta Braves
0 :  1
San Diego Padres

Mar 28, 2025 - MLB

Atlanta Braves
3 :  4
San Diego Padres

Mar 27, 2025 - MLB

Atlanta Braves
4 :  7
San Diego Padres

Mar 24, 2025 - MLB Spring Training

Seattle Mariners
7 :  7
San Diego Padres
W W L W L D
Victories

3/6 (50%)

Defeats

3/6 (50%)

Mar 23, 2025 - MLB Spring Training

San Diego Padres
5 :  5
Arizona Diamondbacks

Mar 22, 2025 - MLB Spring Training

San Diego Padres
8 :  12
Cleveland Guardians

Mar 21, 2025 - MLB Spring Training

San Diego Padres
5 :  1
Chicago Cubs

Mar 18, 2025 - MLB Spring Training

San Diego Padres
3 :  4
San Francisco Giants

Mar 16, 2025 - MLB Spring Training

San Diego Padres
4 :  2
Los Angeles Angels

Mar 15, 2025 - MLB Spring Training

San Diego Padres
8 :  3
Seattle Mariners

Cleveland Guardians against San Diego Padres : Head to Head (H2H)

Cleveland Guardians

33 %

San Diego Padres

67 %

Mar 31, 2025 - MLB

Cleveland Guardians
2 :  7
San Diego Padres

Mar 22, 2025 - MLB Spring Training

San Diego Padres
8 :  12
Cleveland Guardians

Mar 8, 2025 - MLB Spring Training

Cleveland Guardians
2 :  7
San Diego Padres

Jul 21, 2024 - MLB

San Diego Padres
2 :  1
Cleveland Guardians

Jul 20, 2024 - MLB

San Diego Padres
7 :  0
Cleveland Guardians

Jul 19, 2024 - MLB

San Diego Padres
0 :  7
Cleveland Guardians

Cleveland Guardians - San Diego Padres Key Points

  1. Allen allowed two home runs in his last two official starts
  2. King failed to throw 100 pitches in any of his last five outings
  3. Seven of the Guardians' last 10 games resulted in a Game Total of OVER
  4. The Padres' 2024 record as home betting favorites was 38-29

Our Cleveland Guardians vs San Diego Padres Prediction

The Padres' bats undeniably started the 2025 season well without the need to give up too many home runs. Merrill, the best rookie hitter in 2024, is slotted in as the fourth spot between Machado and Cronenworth. However, the Guardians lineup is also known for making runs in every possible way, and King won't have an easy time navigating the game. Our prediction for Padres vs Guardians is: Over 7.5 runs.

Prediction:

 

Over 7.5 runs.

-114
$150 offered for betting!

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Cleveland Guardians vs San Diego Padres Picks