Cleveland Guardians vs Pittsburgh Pirates Prediction & Picks - MLB

USA - MLB

Cleveland Guardians
4/18/25 18:40
Pittsburgh Pirates

Prediction:

 

Guardians ML.

-119
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 by Carlos Zabala | in MLB Picks

The Pirates don't want to sink to the bottom of their division so early, and by winning a series against the Cardinals and then a four-game series, 3-1, against the Nationals, their record is now 8-12 and a 6-4 win at PNC Park.

Without a break, the Pirates face another series in Pittsburgh, hosting the Guardians. They will also play back-to-back games, but they will play after 6 p.m. on Thursday.

The Pirates started the series against the Nats by scoring 10 runs in uncharacteristic fashion, ultimately giving offensive support to Skenes, who earned his second W. The Pirates then lost the game 2, won the third game 6-1, and took the final game, also winning 1-0 thanks to Cruz's solo home run, his fourth of the season. The Pirates started as a -150 favorite to win that game, in which only 10 hits were scored between the two teams.

The Guardians last visited PNC Park in 2023, and they fared quite well, winning the series 2-1 and scoring 10 or more runs in two games. The Guardians have crushed their division rivals this season but have lost all three games against the Padres, the only NL team they have faced in 2025.

Cleveland Guardians vs Pittsburgh Pirates Form

Table

Teams % P W L
13
Cleveland Guardians
Cleveland Guardians
0.526 19 10 9
24
Pittsburgh Pirates
Pittsburgh Pirates
0.381 21 8 13

Cleveland Guardians and Pittsburgh Pirates Latest Matches

Cleveland Guardians
Cleveland Guardians Latest matches
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 17, 2025 - MLB

Cleveland Guardians
2 :  6
Baltimore Orioles

Apr 16, 2025 - MLB

Cleveland Guardians
1 :  9
Baltimore Orioles

Apr 15, 2025 - MLB

Cleveland Guardians
6 :  3
Baltimore Orioles

Apr 13, 2025 - MLB

Kansas City Royals
4 :  2
Cleveland Guardians

Apr 12, 2025 - MLB

Kansas City Royals
3 :  6
Cleveland Guardians

Apr 11, 2025 - MLB

Kansas City Royals
0 :  7
Cleveland Guardians
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 13, 2025 - MLB

Kansas City Royals
4 :  2
Cleveland Guardians

Apr 12, 2025 - MLB

Kansas City Royals
3 :  6
Cleveland Guardians

Apr 11, 2025 - MLB

Kansas City Royals
0 :  7
Cleveland Guardians

Apr 10, 2025 - MLB

Chicago White Sox
1 :  6
Cleveland Guardians

Apr 9, 2025 - MLB

Chicago White Sox
2 :  3
Cleveland Guardians

Apr 8, 2025 - MLB

Chicago White Sox
0 :  1
Cleveland Guardians
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 17, 2025 - MLB

Cleveland Guardians
2 :  6
Baltimore Orioles

Apr 16, 2025 - MLB

Cleveland Guardians
1 :  9
Baltimore Orioles

Apr 15, 2025 - MLB

Cleveland Guardians
6 :  3
Baltimore Orioles

Apr 6, 2025 - MLB

Cleveland Guardians
2 :  6
Los Angeles Angels

Apr 5, 2025 - MLB

Cleveland Guardians
4 :  10
Los Angeles Angels

Apr 4, 2025 - MLB

Cleveland Guardians
8 :  6
Los Angeles Angels
Pittsburgh Pirates
Pittsburgh Pirates Latest matches
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 17, 2025 - MLB

Washington Nationals
0 :  1
Pittsburgh Pirates

Apr 16, 2025 - MLB

Washington Nationals
1 :  6
Pittsburgh Pirates

Apr 15, 2025 - MLB

Washington Nationals
3 :  0
Pittsburgh Pirates

Apr 14, 2025 - MLB

Washington Nationals
3 :  10
Pittsburgh Pirates

Apr 13, 2025 - MLB

Pittsburgh Pirates
0 :  4
Cincinnati Reds

Apr 12, 2025 - MLB

Pittsburgh Pirates
2 :  5
Cincinnati Reds
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 17, 2025 - MLB

Washington Nationals
0 :  1
Pittsburgh Pirates

Apr 16, 2025 - MLB

Washington Nationals
1 :  6
Pittsburgh Pirates

Apr 15, 2025 - MLB

Washington Nationals
3 :  0
Pittsburgh Pirates

Apr 14, 2025 - MLB

Washington Nationals
3 :  10
Pittsburgh Pirates

Apr 9, 2025 - MLB

St. Louis Cardinals
1 :  2
Pittsburgh Pirates

Apr 8, 2025 - MLB

St. Louis Cardinals
5 :  3
Pittsburgh Pirates
L L W L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 13, 2025 - MLB

Pittsburgh Pirates
0 :  4
Cincinnati Reds

Apr 12, 2025 - MLB

Pittsburgh Pirates
2 :  5
Cincinnati Reds

Apr 11, 2025 - MLB

Pittsburgh Pirates
3 :  5
Cincinnati Reds

Apr 2, 2025 - MLB

Pittsburgh Pirates
4 :  2
Tampa Bay Rays

Apr 1, 2025 - MLB

Pittsburgh Pirates
0 :  7
Tampa Bay Rays

Mar 31, 2025 - MLB

Pittsburgh Pirates
1 :  6
Tampa Bay Rays

Cleveland Guardians against Pittsburgh Pirates : Head to Head (H2H)

Cleveland Guardians

67 %

Pittsburgh Pirates

33 %

Sep 1, 2024 - MLB

Pittsburgh Pirates
1 :  6
Cleveland Guardians

Aug 31, 2024 - MLB

Pittsburgh Pirates
3 :  0
Cleveland Guardians

Aug 30, 2024 - MLB

Pittsburgh Pirates
8 :  10
Cleveland Guardians

Jul 18, 2023 - MLB

Cleveland Guardians
10 :  1
Pittsburgh Pirates

Sep 27, 2020 - MLB

Pittsburgh Pirates
6 :  8
Cleveland Guardians

Sep 26, 2020 - MLB

Pittsburgh Pirates
8 :  0
Cleveland Guardians

Cleveland Guardians - Pittsburgh Pirates Key Points

  1. The Pirates won two straight games against the Nationals for the second time this season
  2. Pirates' collective AVG is worst in MLB at 197 in 2025
  3. Pirates' 3-2 record this season as home underdog
  4. As of Thursday, the Guardians' Kwan had a 313 AVG

Our Cleveland Guardians vs Pittsburgh Pirates Prediction

Friday's Pirates-Guardians game will be a game between high-ERA pitchers. Luis Ortiz pitched 16.1 innings for the Guardians with a 6.06 ERA, but the Pirates' pitcher's numbers are quite similar, with a 6.23 ERA in 13.0 IP. Neither pitcher has previously faced the team they will face on Friday, while Ortiz has allowed three home runs this season. Carmen Mlodzinski of the Pirates has yet to concede his first home run. Our prediction for Pirates vs Guardians is: Guardians ML.

Prediction:

 

Guardians ML.

-119
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Cleveland Guardians vs Pittsburgh Pirates Picks