USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Travis Pulver in MLB Picks
The Cincinnati Reds will try to get things turned around as they head to San Francisco for a three-game series vs. the Giants. Game One is scheduled to get underway tonight at 9:45 p.m. EST.
It has certainly been a struggle for the Reds so far this season. They have managed to win one in each series (they’ve played three), and that’s it. After making history with three consecutive 1-0 losses, they lost a fourth straight game but scored two runs (3-2). Their bats finally woke up against the Brewers on Saturday for 14 hits and 11 runs, but then it came crashing back down to Earth in the series finale Sunday in an 8-2 loss. San Francisco’s only loss of the season came in their season-opening series vs. the Reds in Cincinnati (Game Two, 3-2). They have since gone 7-0 and sit in first place in the NL West, a game above the LA Dodgers.
The Reds will give the ball to Hunter Greene tonight. He started the season opener against the Giants, lasting five innings and giving up three hits, including a home run, and two runs while striking out eight. Greene was also the pitcher for one of the 1-0 losses (vs. Texas, seven innings, three hits, one run, eight strikeouts). San Francisco is going with Logan Webb, who started the season opener vs. Greene but didn’t factor into the decision.
Limited Offer. Currently at DraftKings
Cincinnati Reds vs San Francisco Giants Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
2
![]() |
0.643 | 28 | 18 | 10 |
11
![]() |
0.519 | 27 | 14 | 13 |
Cincinnati Reds and San Francisco Giants Latest Matches

1/6 (17%)
5/6 (83%)
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Apr 3, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 27, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Apr 3, 2025 - MLB
Mar 22, 2025 - MLB Spring Training
Mar 21, 2025 - MLB Spring Training

6/6 (100%)
0/6 (0%)
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
6/6 (100%)
0/6 (0%)
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB
Mar 25, 2025 - MLB Spring Training
Mar 24, 2025 - MLB Spring Training
Mar 22, 2025 - MLB Spring Training
5/6 (83%)
1/6 (17%)
Apr 2, 2025 - MLB
Apr 1, 2025 - MLB
Mar 31, 2025 - MLB
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 27, 2025 - MLB
Cincinnati Reds against San Francisco Giants : Head to Head (H2H)
17 %
83 %
Mar 30, 2025 - MLB
Mar 29, 2025 - MLB
Mar 27, 2025 - MLB
Feb 23, 2025 - MLB Spring Training
Aug 4, 2024 - MLB
Aug 2, 2024 - MLB
Cincinnati Reds - San Francisco Giants Key Points
- The Giants are off to an 8-1, 3-0 at home start while the Reds are 3-7, 1-3 away.
- San Francisco leads the all-time series vs. Cincinnati 1239-1036-15.
- Cincinnati went 1-2 at home and on the road vs. San Francisco last season.
- 95% of the moneyline tickets and 99% of the handle is on San Francisco.
Limited Offer. Currently at DraftKings
Our Cincinnati Reds vs San Francisco Giants Prediction
When these two pitched in the opener, the teams scored ten runs. But since then, the Reds' lineup has struggled to make contact. San Francisco has been hitting well this season, but Greene did a great job against them in the opener. I’m betting the Reds' bats will go silent again, but Greene will keep the Giants in check. The easy bet here is the Giants ML, but I’m going with something else.
Our Reds vs. Giants Pick: UNDER 7
Claim $200 for your Cincinnati Reds vs San Francisco Giants wager!
Would you like to bet on Cincinnati Reds vs San Francisco Giants? For this MLB match, the sportsbook treats you to an exclusive offer: a bonus of $200, no promo code needed! Take advantage while you still can!
Not registered yet? You can create your account now by filling in this form. A bonus of $200 awaits you on the Cincinnati Reds vs San Francisco Giants match!
All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Limited Offer. Currently at DraftKings