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by Travis Pulver in MLB Picks
The Chicago White Sox will try once again to get their first road win of the season when they take on the Red Sox in Game Two of a four-game series at Fenway Park in Boston, MA. First pitch for this contest is scheduled for 4:10 p.m. EST.
Boston got to Chicago starting pitcher Martin Perez early in Friday’s game, chasing him after three innings, and recording five hits (one home run) and four earned runs off of him. The Chicago bullpen didn’t do much better, giving up six more hits and earned runs over the last six innings of the game. Hunter Dobbins gave the Red Sox six solid innings (three hits, two runs (one earned), and six strikeouts) to earn his second win of the season. The White Sox will turn to Shane Smith on the mound to start the game. Smith is 0-1 in three starts with a 2.04 ERA and a .91 WHIP; he’s received just four runs of support in his three starts. Boston will give the ball to Garrett Crochet to start the game. He’s 2-1 in four starts this season with a 1.38 ERA and .88 WHIP. Crochet went 7 1/3 innings in his last start, recording 11 strikeouts and allowing one hit.
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Chicago White Sox vs Boston Red Sox Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
14
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0.533 | 30 | 16 | 14 |
29
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0.25 | 28 | 7 | 21 |
Chicago White Sox and Boston Red Sox Latest Matches

1/6 (17%)
5/6 (83%)
Apr 18, 2025 - MLB
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2/6 (33%)
4/6 (67%)
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0/6 (0%)
6/6 (100%)
Apr 18, 2025 - MLB
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Apr 5, 2025 - MLB

4/6 (67%)
2/6 (33%)
Apr 18, 2025 - MLB
Apr 16, 2025 - MLB
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Apr 12, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 18, 2025 - MLB
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3/6 (50%)
3/6 (50%)
Apr 16, 2025 - MLB
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Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Chicago White Sox against Boston Red Sox : Head to Head (H2H)
50 %
50 %
Apr 18, 2025 - MLB
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Chicago White Sox - Boston Red Sox Key Points
- The Red Sox lead the all-time series vs. the White Sox 1003-965-11.
- The White Sox are 6-4 in their last ten vs. the Red Sox in Boston.
- The White Sox are 0-7 in road games this season.
- Chicago is 6-8 via the run line after a loss.
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Our Chicago White Sox vs Boston Red Sox Prediction
This game has the makings of a pitching duel. Both pitchers have allowed just four earned runs this season, Crochet in four starts and Smith in three. Boston is hitting .250 over the last week, and Chicago is just .165. Boston has shown some power, though, with ten home runs in that time frame. I’d lean towards the Red Sox winning, but the UNDER is the better bet.
Our White Sox vs. Red Sox Pick: UNDER 8.5
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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