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by Lou Aguila | in MLB Picks
The Boston Red Sox and the Chicago White Sox meet again to begin a new three-game series over the weekend starting on Friday at Fenway Park.
The Red Sox have gone 3-2 in their last five games, including back-to-back wins vs. Tampa Bay, to stay afloat with a 10-10 record in a brutally competitive AL East standings. In the season, Boston is batting .247 with 86 runs and pitching a 4.16 ERA, which puts them in the bottom half of the league.
The White Sox have lost their last four games, including Thursday’s embarrassing 0-8 loss to the Oakland Athletics in the series finale. Like the Red Sox, Chicago’s struggle is rooted from their inability to prevent their opponents from scoring runs. The White Sox’s 4.36 ERA falls in the bottom 10 of the MLB in that category.
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Chicago White Sox vs Boston Red Sox Form
Table
Teams | % | P | W | L |
---|---|---|---|---|
15
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0.524 | 21 | 11 | 10 |
29
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0.211 | 19 | 4 | 15 |
Chicago White Sox and Boston Red Sox Latest Matches

2/6 (33%)
4/6 (67%)
Apr 17, 2025 - MLB
Apr 16, 2025 - MLB
Apr 15, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
2/6 (33%)
4/6 (67%)
Apr 17, 2025 - MLB
Apr 16, 2025 - MLB
Apr 15, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
0/6 (0%)
6/6 (100%)
Apr 10, 2025 - MLB
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 6, 2025 - MLB
Apr 5, 2025 - MLB
Apr 4, 2025 - MLB

3/6 (50%)
3/6 (50%)
Apr 16, 2025 - MLB
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 10, 2025 - MLB
Apr 9, 2025 - MLB
Apr 8, 2025 - MLB
Apr 7, 2025 - MLB
Apr 6, 2025 - MLB
Apr 6, 2025 - MLB
3/6 (50%)
3/6 (50%)
Apr 16, 2025 - MLB
Apr 15, 2025 - MLB
Apr 14, 2025 - MLB
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Chicago White Sox against Boston Red Sox : Head to Head (H2H)
50 %
50 %
Apr 13, 2025 - MLB
Apr 12, 2025 - MLB
Apr 11, 2025 - MLB
Sep 8, 2024 - MLB
Sep 7, 2024 - MLB
Sep 6, 2024 - MLB
Chicago White Sox - Boston Red Sox Key Points
- Chicago White Sox is 2-12 SU in its last 14 games.
- Chicago White Sox is 0-6 SU in its last 6 games on the road.
- Boston is 12-6 SU in its last 18 games played in April.
- Boston is 1-5 SU in its last 6 games played on a Friday.
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Our Chicago White Sox vs Boston Red Sox Prediction
The Red Sox enter the weekend series with the White Sox eager to get even, having lost to Chicago in 2 out of 3 games in the previous series. The White Sox are starting Martin Perez, who allowed two earned runs in 4.1 innings of a 3-2 win over the Red Sox on April 12. He will match up against Hunter Dobbins, who surrendered two earned runs in 5.0 innings in his MLB debut. The Red Sox have the momentum heading to Game 1 because of their two-game win streak. However, their scoring woes, averaging 2.8 runs per game in their last five assignments, make them an unattractive pick to cover -1.5 runs. I could place a bet on them winning, but at -210, I would rather bite the bullet and put in a stake at the White Sox to lose by at least one run because of its payout upside at -120. Our betting prediction for Chicago White Sox vs. Boston Red Sox: White Sox +1.5 runs.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

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