Boston Red Sox vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Boston Red Sox
4/26/25 18:10
Cleveland Guardians

Prediction:

 

Guardians will win

-105
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 by Lou Aguila in MLB Picks

The Boston Red Sox and the Cleveland Guardians kick off their weekend series on Friday at Progressive Field.

The Red Sox are 2-3 in their last five games, including back-to-back losses to the Seattle Mariners this week. Boston parades strong batting numbers, averaging .244 at the plate with 124 runs. Unfortunately, they fall in the lower half of the league with an ERA of 4.06.

The Guardians had their five-game win streak snapped on Wednesday after a 1-5 loss to the New York Yankees. Nevertheless, Cleveland got 2 wins out of 3 games in that series to up their record to 14-10. The Guardians are batting .235 with 96 runs and pitching a 3.94 ERA this season. They will be sending Ben Lively (1-2, 3.86 ERA) to the mound to go up against Red Sox’s starter Tanner Houck (0-2, 7.66 ERA).

Boston Red Sox vs Cleveland Guardians Form

Table

Teams % P W L
7
Cleveland Guardians
Cleveland Guardians
0.583 24 14 10
13
Boston Red Sox
Boston Red Sox
0.519 27 14 13

Boston Red Sox and Cleveland Guardians Latest Matches

Boston Red Sox
Boston Red Sox Latest matches
W L W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 24, 2025 - MLB

Seattle Mariners
4 :  3
Boston Red Sox

Apr 23, 2025 - MLB

Seattle Mariners
8 :  5
Boston Red Sox

Apr 22, 2025 - MLB

Seattle Mariners
3 :  8
Boston Red Sox

Apr 21, 2025 - MLB

Chicago White Sox
2 :  4
Boston Red Sox

Apr 20, 2025 - MLB

Chicago White Sox
8 :  4
Boston Red Sox

Apr 19, 2025 - MLB

Chicago White Sox
3 :  4
Boston Red Sox
W L W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 24, 2025 - MLB

Seattle Mariners
4 :  3
Boston Red Sox

Apr 23, 2025 - MLB

Seattle Mariners
8 :  5
Boston Red Sox

Apr 22, 2025 - MLB

Seattle Mariners
3 :  8
Boston Red Sox

Apr 21, 2025 - MLB

Chicago White Sox
2 :  4
Boston Red Sox

Apr 20, 2025 - MLB

Chicago White Sox
8 :  4
Boston Red Sox

Apr 19, 2025 - MLB

Chicago White Sox
3 :  4
Boston Red Sox
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 16, 2025 - MLB

Boston Red Sox
1 :  0
Tampa Bay Rays

Apr 15, 2025 - MLB

Boston Red Sox
7 :  4
Tampa Bay Rays

Apr 14, 2025 - MLB

Boston Red Sox
1 :  16
Tampa Bay Rays

Apr 13, 2025 - MLB

Boston Red Sox
3 :  1
Chicago White Sox

Apr 12, 2025 - MLB

Boston Red Sox
2 :  3
Chicago White Sox

Apr 11, 2025 - MLB

Boston Red Sox
1 :  11
Chicago White Sox
Cleveland Guardians
Cleveland Guardians Latest matches
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 23, 2025 - MLB

New York Yankees
5 :  1
Cleveland Guardians

Apr 22, 2025 - MLB

New York Yankees
2 :  3
Cleveland Guardians

Apr 21, 2025 - MLB

New York Yankees
4 :  6
Cleveland Guardians

Apr 20, 2025 - MLB

Cleveland Guardians
5 :  4
Pittsburgh Pirates

Apr 19, 2025 - MLB

Cleveland Guardians
3 :  0
Pittsburgh Pirates

Apr 18, 2025 - MLB

Cleveland Guardians
10 :  7
Pittsburgh Pirates
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 23, 2025 - MLB

New York Yankees
5 :  1
Cleveland Guardians

Apr 22, 2025 - MLB

New York Yankees
2 :  3
Cleveland Guardians

Apr 21, 2025 - MLB

New York Yankees
4 :  6
Cleveland Guardians

Apr 13, 2025 - MLB

Kansas City Royals
4 :  2
Cleveland Guardians

Apr 12, 2025 - MLB

Kansas City Royals
3 :  6
Cleveland Guardians

Apr 11, 2025 - MLB

Kansas City Royals
0 :  7
Cleveland Guardians
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 20, 2025 - MLB

Cleveland Guardians
5 :  4
Pittsburgh Pirates

Apr 19, 2025 - MLB

Cleveland Guardians
3 :  0
Pittsburgh Pirates

Apr 18, 2025 - MLB

Cleveland Guardians
10 :  7
Pittsburgh Pirates

Apr 17, 2025 - MLB

Cleveland Guardians
2 :  6
Baltimore Orioles

Apr 16, 2025 - MLB

Cleveland Guardians
1 :  9
Baltimore Orioles

Apr 15, 2025 - MLB

Cleveland Guardians
6 :  3
Baltimore Orioles

Boston Red Sox against Cleveland Guardians : Head to Head (H2H)

Boston Red Sox

33 %

Cleveland Guardians

67 %

Apr 25, 2024 - MLB

Boston Red Sox
4 :  6
Cleveland Guardians

Apr 24, 2024 - MLB

Boston Red Sox
8 :  0
Cleveland Guardians

Apr 23, 2024 - MLB

Boston Red Sox
1 :  4
Cleveland Guardians

Apr 18, 2024 - MLB

Cleveland Guardians
5 :  4
Boston Red Sox

Apr 17, 2024 - MLB

Cleveland Guardians
0 :  2
Boston Red Sox

Apr 16, 2024 - MLB

Cleveland Guardians
10 :  7
Boston Red Sox

Boston Red Sox - Cleveland Guardians Key Points

  1. Cleveland is 4-1 SU in its last 5 games when playing at home against Boston.
  2. Cleveland is 7-2 SU in its last 9 games at home.
  3. Boston is 6-3 SU in its last 9 games.
  4. Boston is 1-4 SU in its last 5 games when playing on the road against Cleveland.

Our Boston Red Sox vs Cleveland Guardians Prediction

Fearless Forecast: Guardians draw first blood behind another strong outing from Ben Lively.

Ben Lively has scored two shutouts in his last three starts, including a five-inning shutdown of the Pirates on April 19. I expect Lively to pitch strongly against a team he’s averaging 2.0 earned runs over his last three starts. Houck carries a 7.66 ERA largely because of her miserable stint vs. Tampa Bay on April 14, in which he allowed 11 earned runs in 2.1 innings pitched. Moreover, Cleveland is 4-1 SU in its last five games when playing against Boston and 5-4 against the spread at home. Our betting prediction for the Cleveland Guardians vs. Boston Red Sox: Guardians -1.5 Runs.

Prediction:

 

Guardians will win

-105
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Boston Red Sox vs Cleveland Guardians Picks